Loading...
 

Senior Scientist - Spatial Mass Spectrometry

Facility:  Research
Location: 

Seattle, WA, US

About the Department                                                                                                                                             

At Novo Nordisk Research Center Seattle, Inc. (NNRCSI) our scientists apply cutting-edge technologies to early R&D projects with the goal of bringing real change to people with Diabetes and Obesity. Our scientists apply state-of-the-art technologies within the diabetes and obesity areas, with the goal of bringing molecules to market. Your skills, dedication and ambition will help change lives for the better and you will work with extraordinary talent, continuously learn and develop, and drive changes to defeat serious chronic conditions. We recognize the importance of an enjoyable workplace, which stimulates a strong culture of ingenuity and innovation and our support of a healthy work-life balance adds to a best-in-class employee experience. The team is comprised of collaborative, diverse and passionate people who have a true sense of pride in their work and are committed to helping others grow and develop in their careers. You’ll also have a platform to engage with key stakeholders on a global scale throughout the entire pipeline process. And while changing the future of obesity treatment is no easy task, we also recognize the importance of an enjoyable workplace, which is why we’ve cultivated a culture of fun, ingenuity and innovation. We are changing lives, are you ready to make a difference?

 

The Position

The Sr Scientist, Spatial Mass Spectrometry, will contribute to the development of a state-of-the-art multiomics platform to accelerate discovery and validation of new therapeutic targets for chronic metabolic disease. This person will bring expertise and experience in the development and application of advanced Mass Spectrometry techniques to the molecular profiling of cells and tissues in order to elucidate novel mechanisms of human disease biology. This person will be a key member of the Advanced Omics team and will be involved in cross-functional research activities and project teams across the global drug discovery organization. This person will represent the organization to the external scientific community through publication and presentation of research, and through development, management, and leadership of external collaborations. This individual will be seen across the company as a subject matter expert in the area of Mass Spectrometry multiomics and spatial biology.

 

Relationships

Reports to the head of the Advanced Omics department within Type 1 Diabetes and Kidney Disease at Novo Nordisk Research Center Seattle. 

Internal relationships include working closely with technical staff & other members of the scientific leadership team; regular collaborations with members of other research departments at NNRCSI; & frequent interaction with project managers & other colleagues across global R&D. Individual may direct the work of other staff members.  Individual will interact with external research collaborators both academia- & industry-based.

 

Essential Functions

  • Major contributor to research projects through independent work involving highly complex activities, receiving minimal guidance. Leads research projects involving coordination of multiple experimental activities and groups, recommends and is responsible for ensuring realistic project timelines and deliverables, and works closely with local or global project managers.
  • Demonstrates subject matter expertise and in-depth experience, as well as creative, independent thinking to identify and address disease/biology-related questions/gaps, potentially across therapeutic areas.
  • Analyzes complex data with high degree of sophistication, connecting disparate datasets to reach conclusions, and set direction on experiments. Contributes strong scientific acumen to enable projects and advance the research agenda. Authors internal reports and external publications.
  • Effectively communicates and collaborates across global sites and guides project strategy by providing expert input to cross-functional project teams. Represents the organization at scientific conferences and global meetings by authorship and publication of scientific papers and patents. Proposes, manages, and may lead external collaborations.
  • Maintains a strong understanding of theoretical knowledge and a connection to the external scientific community through continuous evaluation of relevant literature. Expands the capabilities of early target discovery through the generation of new target ideas, evaluation of biology or methods, and implementation of technologies that add value.
  • Leads cross-functional experimental teams to achieve project goals, mentor junior staff, and provide training. Acts as a resource for colleagues with less experience; may direct the work of other staff members.
  • Influences the research pipeline by recommending, presenting, and championing new targets or methodologies.
  • Works with Department Heads and Scientists to ensure better practice sharing and implementation within the research environment.
  • Demonstrates superior cross-cultural understanding to effectively interact with relevant stakeholders in the global organization.

 

Qualifications

  • Bachelor 's Degree within Biochemistry, Analytical Chemistry, Proteomics or related discipline and 18+ years’ relevant experience required,
  • Doctoral degree in with 6+ years’ post-doctoral and/or industry relevant experience or a master’s degree with 12+ years’ relevant experience can be considered.
  • Relevant required experience includes some combination of: 
    • Experience applying mass spectrometry-based omics for drug discovery applications
    • Experience in operating high-resolution mass spectrometers and analyzing omics data
    • Fundamental knowledge of biostatistics, informatics and computational tools for M/S data analysis
    • Developing and leading innovative discovery programs and cross-functional project teams
  • Preferred experience includes: 
    • Familiarity with multiple data acquisition strategies including DDA, DIA and PRM
    • Familiarity with advanced mass spectrometry imaging techniques and data analysis 
    • Spatial multi-omics data collection and integration
    • Mass Spectrometry-based proteomics, lipidomics or metabolomics
    • Familiarity with tissue-based biology and spatial transcriptomics
    • Experience in systems biology-level or multi-omics data analysis
    • Understanding of chronic metabolic diseases and their underlying pathophysiology.
  • Demonstrates excellent verbal and written communication skills.
  • Demonstrates outstanding project management knowledge, as well as organizational and time-management skills.

 

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

 

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.

 

Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

 

Novo Nordisk requires all new hires to be fully vaccinated against COVID-19 prior to the first date of employment. As required by applicable law, Novo Nordisk will consider requests for reasonable accommodation.

 

If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.