Lead Global Trial Manager

Location: Søborg office, Denmark (office‑based)
Function: Global Trial Management – Diabetes and Obesity Clinical Operations
Travel: Up to 10 days per year

As a Lead Global Trial Manager (Lead GTM), you are responsible for the end‑to‑end operational execution of complex global, multi‑country clinical trials, from start‑up through conduct and close‑out. You provide day-2-day operational leadership within the trial, driving execution in complex, ambiguous, or high‑risk settings. You operate with a high degree of autonomy, anticipate operational risks early, and apply sound judgement to protect delivery, quality, and compliance.

You are accountable for execution excellence, advanced operational risk management, and delivery predictability within Clinical Operations, and you contribute actively to strengthening trial execution capability across the organisation through mentoring, knowledge sharing, and continuous improvement.

Your new role

Trial delivery & execution

• Lead operational delivery of complex or high‑impact clinical trials across start‑up, conduct, and close‑out, ensuring timelines, quality, and disciplined execution.
• Translate protocol intent and development priorities into robust, executable operational plans across countries and functions.
• Proactively identify, assess, and manage operational risks (including RACT), applying risk‑based judgement and escalating early with clear context and solution options.
• Create, review, and oversee key trial‑level operational documents, including CTA packages, protocol‑related and submission documents, and patient‑ and site‑facing materials.
• Prepare, lead, and contribute to Monitor Meetings and Investigator Meetings, ensuring clear decisions and follow‑up.

Trial squad & cross‑functional leadership

• Provide operational leadership within the trial squad, partnering with Clinical Operations and functions such as Medical & Science, Regulatory, Data Management, Safety Surveillance, Clinical Supplies, and Quality.
• Drive clarity and alignment through structured planning, outcome‑driven meetings, and disciplined follow‑up.

Country, site & recruitment delivery

• Provide operational leadership across participating countries to drive start‑up, enrolment, and trial conduct.
• Closely monitor recruitment performance, anticipate enrolment risks, and drive timely mitigation actions when trajectories deviate.
• Enable effective site delivery through early issue identification, decisive resolution, and alignment to trial expectations.

Vendors, quality & compliance

• Lead oversight of vendors and external partners, ensuring performance against agreed scope, timelines, and quality expectations.
• Ensure trial execution consistently complies with ICH‑GCP, applicable regulations, and internal standards.
• Maintain inspection readiness through strong execution discipline and effective cross‑functional follow‑up.

Capability building & continuous improvement

• Identify and drive practical improvements that simplify execution, reduce friction, and improve predictability across trials.
• Actively share learnings and best practices across Clinical Operations.
• Mentor and support Global Trial Managers, contributing to capability development and consistent ways of working.

How success is measured

Success in the Lead GTM role is defined by outcomes and sustained impact:

• Predictable delivery of complex trials: Key milestones are achieved through early anticipation of risk and proactive intervention.
• Advanced operational judgement: Risks and issues are handled decisively, balancing speed, quality, and compliance.
• Inspection readiness and quality: Execution consistently meets regulatory and quality expectations across the trial lifecycle.
• Recruitment leadership: Enrolment risks are anticipated early and effectively mitigated.
• Strong trial squad leadership: Stakeholders experience clarity, confidence, and strong operational partnership.
• Capability impact: Trial learnings and improvements are translated into stronger ways of working beyond individual trials.

Your skills and Qualifications

• Master’s or bachelor’s degree in life sciences or a related field.
• 5+ years of experience in clinical trial operations, with demonstrated ability to independently lead global or multi‑country clinical trials of varying complexity.
• Strong, applied understanding of ICH‑GCP (certification), regulatory requirements, and operational quality expectations.
• Demonstrated ability to manage complex trial execution with a high degree of autonomy and sound judgement.
• Proven capability to mentor and support other Global Trial Managers and contribute to capability development within Clinical Operations.
• Structured, pragmatic mindset with strong ownership in ambiguous and high‑pressure situations.
• Strong interest in optimising trial execution using digital tools, including AI.
• Professional proficiency in spoken and written English.

Working at Novo Nordisk

Every day we seek solutions that defeat serious chronic diseases. To do this, we approach our work with an unconventional spirit, rare determination, and constant curiosity. For over 100 years, this unordinary mindset has seen us build a company unlike any other. One where a collective passion for our purpose, mutual respect and a willingness to go beyond what we know delivers extraordinary results.

What we offer

There is, of course, more on offer here than the uniqueness of our culture and the extraordinary results we produce. Being part of a global healthcare company means opportunities to learn and develop are all around us, while our benefits are designed with your career and life stage in mind.

Salary:
For this role, the Annual Base Salary ranges from 651,000 DKK to 956,900 DKK, corresponding to Job Level 7.
The placement within the salary range will be assessed during the recruitment process based on the candidate’s skills, competencies, knowledge, and relevant experience.

Incentives and Benefits:
The salary package may include short‑term and/or long‑term incentives as well as other employee benefits based on position level, location, functional area and relevant market benchmarks.

Learn more about our Reward Philosophy here.

Deadline 

26th May, 2026

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