Senior Manager Clinical Operations

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Senior Manager Clinical Operations

Location: Mississauga, Ontario

Office based role (Hybrid)

Function: Clinical Development

About the role

We are looking for a Senior Manager Clinical Operations to act as the strategic driver of operational excellence, productivity, and resource optimization within the Clinical Development Centre (CDC). This role combines people leadership with specialist operational expertise, making you both accountable for team performance and responsible for driving operational excellence.

In this role, you will partner closely with senior clinical leadership to translate strategy into execution, ensuring the organization is equipped with the right capabilities, workforce, vendor landscape, and financial oversight to deliver high-quality clinical outcomes.

This position combines strategic leadership, data-driven decision-making, and strong cross-functional influence in a highly matrixed global environment.

Key responsibilities

Business Operations & Performance Leadership

• Lead CDC business operations by driving workforce and capacity planning, productivity optimization, and performance management.
• Translate global and regional strategies into local execution in close collaboration with the Director, CDC and senior clinical leaders.
• Own and drive data-driven decision-making, defining and monitoring key performance metrics to improve operational readiness and efficiency.
• Act as the local subject-matter expert for Clinical Business Operations, contributing actively to the IO Business Operations community across regions.
• Oversee planning, management, and tracking of non-trial (departmental) budgets, ensuring financial transparency and optimal resource allocation.
• The role includes driving the end-to-end delivery of larger annual CDC events, from strategic direction through to on-the-day execution

Vendor Management Oversight

• Provide strategic oversight of clinical vendors (FSP, FSO, and other trial/non-trial vendors).
• Lead vendor selection, onboarding, performance monitoring, compliance, and escalation management.
• Ensure vendor performance aligns with CDC strategy, contractual commitments, and quality standards.

Clinical Legal & Payments Oversight

• Oversee clinical trial site payments, ensuring accuracy, timeliness, and compliance with budgets, contracts, and internal policies.
• Act as the main local point of contact for Legal, Ethics, and Compliance (LEC) initiatives related to CDC operations.
• Ensure local support functions deliver optimal value aligned with CDC strategy.

Quality & Compliance

• Ensure business operations processes comply with ICH-GCP guidelines, external regulations, and internal policies.
• Drive continuous improvement and operational excellence across CDC support functions.

Who you are

• You bring 8–15+ years of relevant experience in business operations, financial planning, clinical development, or similar roles within the pharmaceutical or biopharmaceutical industry.
• You are a strategic thinker with a strong execution mindset, experienced in translating complex strategies into measurable outcomes.
• You have proven experience working in complex, matrixed organizations, influencing senior stakeholders across functions.
• You are highly analytical, comfortable leveraging data and insights to guide decisions and improve performance.
• You demonstrate strong leadership, communication, and stakeholder management skills across all organizational levels.
• You hold a Bachelor’s degree in Life Sciences, Business, Finance, Health Sciences, or related field; advanced degree (MBA/Master’s) is preferred.
• Fluent in English; additional languages are a plus depending on local requirements.

Working at Novo Nordisk

Every day we seek the solutions that defeat serious chronic diseases. To do this, we approach our work with an unconventional spirit, a rare determination and a constant curiosity. For over 100 years this unordinary mindset has seen us build a company unlike any other. One where a collective passion for our purpose, mutual respect and a willingness to go beyond what we know delivers extraordinary results.

What we offer  

At Novo Nordisk, you’ll join a global healthcare company with a unique culture and strong results. We offer continuous learning, career development, and benefits tailored to your life and career stage. 

Salary: For this role, the annual base salary ranges from $136,310.00  - $ 186,310.00. The placement in the salary range will be assessed during the recruitment process based on your skills, competencies, and knowledge, and how your relevant experience matches the position requirements. 

Benefits: The eligibility for specific benefits may vary based on the job and location. 

Learn more about our Reward Philosophy here. 

More information 

This job posting is for a new full time employee.

For more information, visit novonordisk.com, Facebook, Instagram, X, LinkedIn, and YouTube. 

To complete your application, click “Apply now,” attach your CV, and follow the instructions. 

Application Deadline: May 15th, 2026

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk, we're not chasing quick fixes – we're creating lasting change for long-term health. For over 100 years, we've been driven by a single purpose: to defeat serious chronic diseases and help millions of people live healthier lives. This dedication fuels our constant curiosity and inspires us to push the boundaries of what's possible in healthcare. We embrace diverse perspectives, seek out bold ideas, and build partnerships rooted in shared purpose. Together, we're making healthcare more accessible, treating and preventing diseases, and pioneering solutions that create change spanning generations. When you join us, you become part of something bigger – a legacy of impact that reaches far beyond today.