Senior Scientist, Quantitative Systems Pharmacology

PKPD & QSP

Måløv, Denmark

Do you want to help shape how mathematical modelling informs drug discovery and development? We are looking for a scientist with strong modelling capabilities and a solid foundation in pharmacokinetics and pharmacodynamics (PKPD) to join our growing modelling department within Research & Development at Novo Nordisk.

Your new role:

In this role, you will apply your expertise in modelling and simulation across key therapeutic areas, working closely with subject matter experts across Research & Development. You will contribute to advancing QSP and PKPD capabilities while supporting cross-functional initiatives across the organisation.

• Execute scientific strategies for Quantitative Systems Pharmacology (QSP) and PKPD in collaboration with key stakeholders
• Develop and apply QSP and PKPD models to support decision-making across discovery and development projects
• Translate preclinical PK/PD findings into human predictions and inform candidate progression and clinical dosing strategies
• Prepare study protocols, technical reports, and modelling documentation, including contributions to regulatory submissions
• Integrate diverse datasets (in vitro, in vivo, literature, and competitor data) to generate actionable insights
• Adopt and apply relevant AI tools to enhance scientific workflows and ways of working

Your new department

The PKPD and QSP department is expanding to support a broad portfolio across diabetes and obesity, haemophilia, growth disorders, and rare diseases. Our work focuses on deepening the understanding of disease and treatment mechanisms while informing key development decisions such as dose selection and combination strategies.

You will join a team of highly skilled colleagues working across early discovery, non-clinical, and early clinical development. We collaborate closely with global Discovery and Development teams and external partners, applying pharmacokinetic, pharmacodynamic, and mechanistic modelling approaches to support the pipeline.

Your skills and qualifications:

You hold a PhD in physics, mathematics, engineering, or a related discipline within quantitative biology or pharmacology, combined with relevant postdoctoral experience, ideally within the pharmaceutical or biotech industry.

To succeed in this role, you bring:

• Strong understanding of PKPD, modelling approaches, statistical methods, and data interpretation
• Proven ability to identify scientific challenges and translate them into actionable strategies
• Experience modelling biological or natural systems using mechanistic or hybrid models
• Hands-on experience with modelling tools such as NONMEM, Monolix, or Phoenix WinNonlin, and programming in R, Python, Julia, or MATLAB
• Ability to clearly communicate modelling results and their implications for project decisions
• Experience in relevant disease areas, preferably diabetes and obesity

As a person, you are curious, collaborative, and motivated to continuously learn. You build strong relationships across disciplines and communicate effectively in English.

Working at Novo Nordisk

Every day we seek the solutions that defeat serious chronic diseases. To do this, we approach our work with determination, constant curiosity and a commitment to finding better ways forward. For over 100 years, this dedication has driven us to build a company focused on lasting change for long-term health. One where diverse thinking, shared purpose and mutual respect come together to create extraordinary results. When you join us, you're not just starting a job – you're becoming part of a story that spans generations.

What we offer

There is, of course, more on offer here than the uniqueness of our culture and the extraordinary results we produce. Being part of a global healthcare company means opportunities to learn and develop are all around us, while our benefits are designed with your career and life stage in mind.

Salary: For this role, the Annual Base Salary ranges from 651,000.00 to 956,900.00 DK (DKK), corresponding to the level of the position.

The placement within the salary range will be assessed during the recruitment process based on the candidate’s skills, competencies, knowledge, and relevant experience.

Incentives and Benefits: The salary package may include short-term and/or long-term incentives as well as other employee benefits based on position level, location, functional area and relevant market benchmarks.

Learn more about our Reward Philosophy here

Additional information
Due to the high number of applications, we unfortunately do not offer introductory calls prior to the interview stage. However, if you experience any practical challenges related to the application process, you are welcome to contact Talent Acquisition Partner Aleksandra Maria Strzalka Polat at AZZQ@novonordisk.com

Deadline:

30 June 2026 We will evaluate and conduct interviews on an ongoing basis, so please apply as soon as possible.

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk, we're not chasing quick fixes – we're creating lasting change for long-term health. For over 100 years, we've been driven by a single purpose: to defeat serious chronic diseases and help millions of people live healthier lives. This dedication fuels our constant curiosity and inspires us to push the boundaries of what's possible in healthcare. We embrace diverse perspectives, seek out bold ideas, and build partnerships rooted in shared purpose. Together, we're making healthcare more accessible, treating and preventing diseases, and pioneering solutions that create change spanning generations. When you join us, you become part of something bigger – a legacy of impact that reaches far beyond today.