Research Associate - ADME

Facility:  Research

Lexington, MA, US

About the Department

Dicerna, a Novo Nordisk company, is focused on driving innovation in RNAi (ribonucleic acid interference) to selectively target and silence genes that cause or contribute to disease. Our proprietary GalXC™ and GalXC-Plus™ RNAi technologies have the potential to address conditions that are difficult or impossible to treat with other modalities. Established as a Transformational Research Unit (TRU) following Novo Nordisk’s acquisition of Dicerna Pharmaceuticals, Inc. in December 2021, the Dicerna TRU is a unique new organization within Novo Nordisk that brings together the best of both worlds – the agility, collaborative pioneering spirit and calculated risk-taking profile of a biotech along with the scale, resources and capabilities of a global leader in drug development. With approximately 200 researchers, scientists, drug developers and operational staff, we are a team of inventive and entrepreneurial thinkers pushing the boundaries of science to create and drive new RNAi-based therapies for both rare and more prevalent diseases from the bench to the clinic. Together, we are driving change. Are you ready to make a difference?


The Position

We are seeking a Research Associate - Absorption, Distribution, Metabolism and Excretion to help support the development of our growing pipeline of product candidates. The individual in this position will assist in the conduct of nonclinical studies and the ADME assays and sample analysis.



This position reports to the Director, TRU Early Development, Nonclinical and Clinical Pharmacology.


Essential Functions

  • Biological sample preparation for analysis (blood, urine, tissues, and cells)
  • Familiarity with method development, method qualification preferred
  • Generation and interpretation of experimental data, with appropriate documentation
  • Present generated data at group meetings
  • Preparation of dosing formulations and solutions
  • Assist in the conduct of rodent studies
  • Contribute to the preparation of nonclinical components of reports
  • QC data generated withing the nonclinical group


Physical Requirements

0-10% overnight travel required.



  • B.S./M.S. in a scientific discipline, analytical chemistry, chemistry, biochemistry, biotechnology or related discipline preferred, with 0+ years of pharmaceutical industry or CRO experience
  • Experience with Bioanalytical sample analysis techniques (HPLC, PCR and other analytical methods) required
  • Enthusiasm for meeting program timelines and goals
  • Experience working with rodents is a plus
  • Experience performing molecular biology techniques and liquid chromatography
  • Experience with oligonucleotides preferred but not required
  • Proficient in MS Office (Word, Excel, Powerpoint)
  • Strong analytical, verbal and written communication skills, as well as attention to detail
  • Effective organization skills and ability to work in a multi-tasking, fast-paced environment
  • Enthusiasm for working with a team and being a team player


We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.


At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.


Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.


If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.