Principal Data Scientist - Integrated Omics

Facility:  Information Technology & Telecom

Lexington, MA, US

About the Department                                                                                                                                             

Are you enthusiastic about driving the design of next generation healthcare solutions that will change the life of patients with diabetes and other serious chronic diseases? Do you want to be on the cutting edge of science to discover novel therapies and delivery technologies that patients both need and want? 

The Novo Nordisk research center Seattle serves as the foundation of the Novo Nordisk U.S. research and development efforts for diabetes, obesity, liver disease and other therapeutic areas. In addition to discovering new therapies and technologies, our dynamic team of scientists and engineers lead an aspirational charge to pioneer scientific breakthroughs that have the potential to prevent and ultimately cure chronic disease. It is where science and technology intersect, and a vision can become a clinical reality. Are you ready to make a difference?  Then join us as we drive change to defeat chronic disease. 


Who we are?

The AI and Analytics Team is part of Novo Nordisk’s Data Science division, where we apply sophisticated algorithms and machine learning techniques to some of the hardest problems in the discovery and development of new healthcare solutions. By leveraging a blend of scientific, problem-solving, and quantitative skills, we provide superior data insights that empower Novo Nordisk to further develop and deliver life-changing treatments. We work in multidisciplinary teams with strong collaboration across all areas of the organization and engage in external collaborations to ensure access to cutting edge research and technology.  

We believe in the value of a diverse and inclusive culture. Together, we build and grow talent to ensure the development of new solutions. The team is comprised of collaborative, diverse and passionate people who have a true sense of pride in their work.  We are committed to helping each other grow, and we are driven by the opportunity to make a difference in the lives of people living with chronic disease. Everything we do starts and ends with the patient. And, while changing the future of chronic disease treatment, such as diabetes and obesity, is no easy task, we also recognize the importance of an enjoyable workplace, which is why we’ve cultivated a culture of fun, ingenuity, and innovation. Our competitive compensation package and support of a healthy work-life balance all add to a best-in-class employee experience. 


The Position

Recognized as a key global leader both within Novo Nordisk's scientific efforts and outside Novo Nordisk. The Principal Data Scientist [Integrated Omics] sets direction for the business unit's effort towards exploring and creating new technology and being a world leader in data science within our fields. The Principal Data Scientist leverages their extensive domain knowledge in high dimensional omics data collection, processing, and analyses as well as software engineering in a data science context, to influence the direction of research in Clinical Data Science at Novo Nordisk. The Principal Data Scientist will guide multiple business units globally in the strategic direction and execution of data science efforts in terms of utilizing large-scale omics datasets to drive drug development. They collaborate with other units to ensure a strong portfolio of research projects, maximizing impact for our patients and business. Moreover, the Principal Data Scientist will actively coach more junior Data Scientists in both professional development and project execution, setting technical direction and influencing the progression of initiatives across Novo Nordisk.



The Principal Data Scientist reports to the Director of Integrated Omics. Internal partners include data scientists, biostatisticians, engineers, software developers, technology scouts & partnership developers, system engineers, designers, anthropologists, medical doctors, IT supports, and others across US and Denmark. External relationships include relationships with commercial and academic collaboration partners.


Essential Functions

  • Scientific work
    • Review progress of initiatives across Novo Nordisk, ensuring data science is being conducted with a high standard and with a strong focus on maximum impact for our stakeholders
    • Lead development, validation and deployment of bioinformatics approaches in the Omics space.
    • Implement and maintain local and cloud-based data and computational environments and platforms and help to integrate data from different sources.
    • Drive implementation of data science best practices across Novo Nordisk, including the performance of data pipelines (data acquisition, preparation, cleaning, and consolidation)
    • Develop web applications to visualize how AI/ML works which may include a complex data visualization as an integral part of data science activity.
    • Identify and propose improvement initiatives that evolve and improve the way the team works and collaborates
    • Serve as an international and company-wide influential thought leader for identification and implementation of omics-based solutions using data science
    • Initiate and lead collaborations with both other Novo Nordisk areas, as well as external collaboration partners in industry and academia
    • Demonstrate initiative in identifying and addressing unmet patient needs using data
    • Prepare and present written and oral reports and proposals to peers and management
    • Generate new ideas and novel concepts towards publishing new patents and scientific papers in support of the relevant research area
    • Drive projects beyond the research phases to potentially clinical research and/or commercialization
  • Collaborative teamwork
    • Leads several cross-functional teams to develop AI and ML solutions
    • Drives virtual global team meetings regularly
    • Collaborates with management to set strategic goals for data science research across Novo Nordisk
    • Achieves business goals, shares learnings, knowledge and skills, and promotes cross-functional teamwork
    • Raise the level of competency in the team by seeking and sharing domain knowledge in the area of Data Science, as well as Novo Nordisk’s therapy areas
    • Actively mentors more junior Data Scientists with an eye on the long-term development of competencies both for the individuals, as well as across Novo Nordisk as a whole
    • Drive the implementation of data science best practices across Novo Nordisk
    • Demonstrates ability to drive frequent collaborations with external commercial and academic partners


Physical Requirements

10-20% overnight travel required.



  • Master’s degree required. PhD preferred. Degree within computer science, molecular biology, chemistry, genetics, computational biology, or a related quantitative discipline preferred.
  • Master’s Degree with 10+ years’ relevant experience or PhD with 6+ years’ relevant experience can be considered
  • Relevant experience includes:
    • Ability to develop and validate algorithms against clinical data, ensuring appropriateness of fit for data science processes.
    • Experience with various bioinformatics approaches, techniques and tools.
    • Extensive experience with working with large-scale omics datasets and across different omics modalities
    • Experience with integrated analyses of multi-omics data to build models and drive biological insights for drug development 
    • Experience with software development which includes writing high quality code processing data using Python, R, or Matlab.
    • Ability to perform in-depth data analysis and present results and conclusions to engineering and leadership teams.
    • Experience in data management, database management system, and familiarity with NoSQL and/or Graph database.
    • Experience in pharmaceutical industry, healthcare industry, regulated medical device development or in another regulated field.
    • Experience with containerization and standard cloud services such as AWS S3, EC2, and Lamba Function.
    • Excellent written and oral communication skills
    • Detail oriented with strong documentation skills

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.


At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.


Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.


Novo Nordisk requires all new hires to be fully vaccinated against COVID-19 prior to the first date of employment. As required by applicable law, Novo Nordisk will consider requests for reasonable accommodation.


If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.