Associate Scientist II - Global Drug Discovery

Facility:  Research
Location: 

Lexington, MA, US

About the Department                                                                                                                                               

Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Seattle reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.

 

The Position

We are seeking a highly motivated and experienced Drug Metabolism and Pharmacokinetics (DMPK) Research Associate II to join our team. The Associate Scientist II will provide scientific and technical expertise within small molecule drug discovery by integrating DMPK strategy to progress drug discovery projects across several therapeutic areas. The Associate Scientist II will support the in vivo and in vitro ADME/PK characterization of new small molecule drug targets, advancing novel therapies to the clinic, and developing technologies to accelerate scientific research. The position includes responsibilities of operational oversight of DMPK studies at CROs with specialized DMPK capabilities . In addition, the Associate scientist will be involved in analyzing and ensuring data integrity, and communicating results from research experiments to project teams. The ideal candidate will possess a Bachelor of Science degree with 8 years of relevant experience or a Master of Science degree with 2 to 4 years of experience in the field.

 

Relationships

Reports to the head of the relevant department at Novo Nordisk Research Center.

Internal relationships include working closely with technical staff & members of the scientific leadership team; regular collaborations with members of other research departments at NNRCSI; & frequent interaction with project managers & other colleagues in Denmark.

Individual may interact with external research collaborators both academia- & industry-based.  Individual Contributor: does not manage other employees or contingent workers.

 

Essential Functions

  • Collaborate with Contract Research Organizations (CROs) to strategize, plan, and analyze in vitro and in vivo studies focused on assessing and refining DMPK profiles of small molecule drug candidates.
  • Experience with identifying/creating Statements of Work (SOWs) with new and existing CROs
  • Analyzes data with high degree of sophistication, connecting disparate datasets to reach conclusions, and suggesting direction on experiments. Responsible for drafting study protocols and reports with limited supervisor input.
  • Facilitate seamless communication within project teams and drive progress towards objectives within a multidisciplinary framework and present scientific findings to interdisciplinary discovery teams.
  • Makes recommendations for new procedures and continuously focuses on optimizing current processes.
  • Partner with Information Technology (IT) to identify and implement platforms and strategies aimed at optimizing ADME/PK data management, tracking, and availability for in silico ADME/DDI modeling platforms.
  • Thrive in a fast-paced, multidisciplinary environment encompassing chemistry, biology, and pharmacology, leveraging external CRO support.

 

Qualifications

  • Bachelor 's Degree and at least 8 years relevant technical experience required; Masters’ degree and at least 4 years relevant experience can be considered.
  • Relevant required experience includes: Excellent understanding of DMPK principles with knowledge of overall study planning and PK modeling
  • Preferred experience includes: Prior experience working in a fully or hybrid DMPK-outsourced models
  • Demonstrates excellent verbal and written communication skills
  • Demonstrates project management knowledge, as well as strong organizational and time-management skills.

 

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

 

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.

 

Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

 

If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.